Studies and clinical trials of bee venom

The beneficial effects of honeybee-venom serum on facial wrinkles in humans
Cell regeneration and wound treatment. (Effects of honeybee (Apis mellifera) venom on keratinocyte migration in vitro)
Biological effects of treatment of an animal skin wound with honeybee (Apis mellifera. L) venom
Bee venom ameliorates compound 48/80-induced atopic dermatitis-related symptoms
Effects of cosmetics containing purified honeybee (Apis mellifera L.) venom on acne vulgaris. 
Inhibitory effects of bee venom on Propionibacterium acnes-induced inflammatory skin disease in an animal model
Bee venom and propolis as a new treatment modality in patients with localized plaque psoriases

Cytolytic nanoparticles attenuate HIV-1 infectivity
Nanoparticles loaded with bee venom (Melittin) kill HIV
The unconventional
idea for an antiviral contraceptive gel

Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections


Harry Perkins Institute of Medical Research study finds honeybee venom rapidly kills aggressive breast cancer cells
Melittin has an anticancer effect on gastric cancer AGS cells and stimulates necrotic cell death in these cells
Bee venom in cancer therapy
​Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells
Anti-cancer effect of bee venom in prostate cancer cells
Bee venom inhibits tumor angiogenesis and metastasis
Nanoparticle ‘Smart Bomb’ To Target Cancer Cells Created From Novel Bee Venom Derivative
Inhibition of mammary carcinoma cell proliferation in vitro and tumor growth in vivo by bee venom
Microarray analysis of gene expression in chondrosarcoma cells treated with bee venom
Antitumor action and immune activation through the cooperation of bee venom secretory
Effect of polypeptides in bee venom on growth inhibition and apoptosis induction
Melittin prevents liver cancer cell metastasis through inhibition of the Rac1-dependent pathway
Bee venom protects hepatocytes from tumor necrosis factor-alpha and actinomycin D
Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation
Influence of honey bee products on transplantable murine tumors
Bee venom inhibits hepatic fibrosis through suppression of pro-fibrogenic cytokine expression

Bee venom reduces arthritis associated edema and nociceptive responses
Bee venom produces antinociceptive and anti-inflammatory effects on rheumatoid arthritis
Bee Venom has anti-arthritic effects
Anti-arthritic effect of bee venom
Sting the pain away 
Effect of bee venom on experimental arthritis
An Overview of Bee Venom Acupuncture in the Treatment of Arthritis
Arthritis by Anthony Di Fabio, about Osteoarthritis and Rheumatoid Disease, including Rheumatoid Arthritis

The analgesic efficacy of bee venom acupuncture for knee osteoarthritis
Effects of bee venom on glutamate-induced toxicity in neuronal and glial cells
Evaluation of bee venom and hyaluronic acid in the intra-articular treatment of osteoarthritis
An overview of bee venom acupuncture in the treatment of arthritis
Bee venom attenuates neuroinflammatory events, extends survival in amyotrophic lateral sclerosis models

Multiple Sclerosis
Bee venom therapy and low dose naltrexone for the treatment of multiple sclerosis
Bee venom extends survival in amyotrophic lateral sclerosis models
A randomized crossover study of bee sting therapy for multiple sclerosis.
Honeybee venom extract as a possible treatment for patients with progressive forms of multiple sclerosis
Bee venom therapy and low dose Naltrexone for the treatment of multiple sclerosis

Melittin restores proteasome function in an animal model of ALS
Bee venom attenuates neuroinflammatory events and extends survival
Melittin restores proteasome function in an animal model of ALS
Effects of Bee Venom on Glutamate-Induced Toxicity in Neuronal and Glial Cells

Temporal Arteritis and Polymyalgia Rheumatic
Electroacupuncture inhibits inflammation reaction – Adjuvant-Induced Arthritis
Antinociceptive effect of bee venom acupuncture inflammatory pain of collagen-induced arthritis

Rheumatoid Arthritis
Clinical randomized study of bee-sting therapy for rheumatoid arthritis
Bee Venom Therapy: Bee Venom, Its Nature, and Its Effect on Arthritic and Rheumatoid Conditions

Bee venom acupuncture for chronic low back pain
Bee venom stimulation reduces cold allodynia
Neuroprotective effects of melittin on hydrogen peroxide-induced apoptotic cell death in neuroblastoma SH-SY5Y cells

Lyme Disease
Bee venom therapy for chronic Lyme disease
The antimicrobial agent melittin exhibits powerful in vitro inhibitory effects on the Lyme disease spirochete
Lyme disease: A Look Beyond Antibiotics
Bee Venom Therapy (BVT) for Chronic Lyme Disease

Ankylosing Spondylitis
Bee venom has been shown to treat Ankylosing Spondylitis (Zaitsev & Poriadin)

Bursitis/Tendinitis (Pain in shoulder, wrist, biceps, leg, knee (patellar), ankle, hip, etc.) 
Therapeutic application of anti-arthritis, pain-releasing of bee venom and its constituent compounds

Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson’s disease
Bee venom has possessed beneficial effects in the treatment of Parkinson disease
Bee venom, a treatment for Parkinson’s disease

Liver fibrosis
Melittin attenuates liver injury in thioacetamide-treated mice through modulating inflammation and fibrogenesis

Bee Venom and Post-Herpetic Neuralgia
Bee stings, a remedy for postherpetic neuralgia? A case report


Scroll to Top